Bioinformatics

This book contains the latest material in the subject, covering next generation sequencing

(NGS) applications and ­meeting the requirements of a complete semester course. This book

digs deep into analysis, providing both concept and practice to satisfy the exact need of

researchers seeking to understand and use NGS data reprocessing, genome assembly, vari-

ant discovery, gene profiling, epigenetics, and metagenomics. The book does not introduce

the analysis pipelines in a black box, but with detailed analysis steps to provide readers

with the scientific and technical backgrounds required to enable them to conduct analysis

with confidence and understanding. The book is primarily designed as a companion for

researchers and graduate students using sequencing data analysis but will also serve as a

textbook for teachers and students in biology and bioscience.